Stephen Nover's NFL Total of the Week
(NFL) Tennessee vs. Indianapolis, 11/29/2020 1:00 PM, Score: 45 - 26
Total: 51.50 | -110.00 Under
Result: Loss
The Colts are a run-first team that will be minus their best running back, Jonathan Taylor, and probably center Ryan Kelly. 
The Titans are going to feed Derrick Henry. They are down to their third-string left tackle with Taylor Lewan and backup Ty Sambrailo both out. Tennessee's next two best offensive lineman, guard Rodger Saffold, and center Ben Jones, are each questionable. 
Indy ranks in the top five in all of the major defensive categories. They held the Titans to 17 points just two weeks ago. Ryan Tannehill had a season-low 5.4 yards per attempt and a 55 percent completion rate in that game. 
Expect a brisk game with the clock constantly moving due to many running plays. The Titans will make sure to clean up their punting and special teams play, which was costly to them in their loss to the Colts two weeks ago.