10* Under Panthers/Saints (1:00 ET): Coming out of a bye is usually considered a luxury, but not if you’re NOT healthy. New Orleans will be without both their starting WRs this week as Michael Thomas is still injured and Emmanuel Sanders tested positive for COVID. This is a Saints team that’s trailed by double digits each of its last two games, both of which were against losing teams (Detroit, Chargers). Whether the injuries cost them a win this week remains up for debate, but I do think that for the 1st time this season we’re about to see a Saints’ game stay Under the total.

Carolina comes in at 3-3, which is better than most would have expected. They were favorites for the first time last week, but lost 23-16 to Chicago and really it wasn’t that close as they got their only TD in the 4th quarter. They were held to a season-low 303 total yards and for the 4th time this season were held to 23 points or fewer. On the bright side, the Panthers’ defense has been steadily improving, holding the L4 opponents to an average of just 19 PPG. They gave up only 261 total yards to the Bears last week, which was the second time in three weeks they allowed less than 300.

I don’t think the Panthers are going to move the ball on the ground very effectively in this game as the Saints defense remains very stout against the run, giving up just 3.6 yards per carry. Remember Carolina lost RB Christian McCaffrey for the season, which is a very big deal! New Orleans knows Carolina QB Teddy Bridgewater well (he played for them LY) and hopefully Bridgewater can provide insight to his own defense on how to stop Drew Brees & the NO offense. These NFC South rivals do have a history of going Over against one another, but this could close as the highest O/U line for one of their games since 2016. The only other time since then we’ve seen a total of 50+, it ended up being a 12-9 final. 10* Under Panthers/Saints