San Francisco vs. Tampa Bay,
09/08/2019 16:25 EDT,
Score: 31 - 17
Point Spread: 0/-110 San Francisco
4 Unit Play. Take #461 San Francisco 49ers over Tampa Bay Buccaneers (4:25p.m., Sunday, September 8 FOX) Just feel that Jameis Winston is a lost cause at quarterback and even Bruce Arians cannot fix him. Jimmy Garoppolo is back healthy and despite not playing well in practice and preseason game he always seems to turn it on when the lights are on. San Francisco is 6-2 when Garoppolo is under center and score over 27 points per game. Tampa Bay is 4-13 ATS in their last 17 games as a home favorite. San Francisco is 6-2 ATS in their last 8 opening games.